QuadraSphere® Microspheres (US Only)
Request InformationPredictable, Flow-Directed Targeting
QuadraSphere Microspheres are calibrated, hydrophilic, & compress up to 80% to facilitate smooth microcatheter delivery.
Features & Benefits
Predictable, Flow-Directed Targeting
QuadraSphere® Microspheres are calibrated, hydrophilic and compress up to 80% to facilitate smooth microcatheter delivery. Once through the microcatheter, they rebound to their stated spherical shape with a consistent cross-sectional diameter for predictable, flow-directed targeting.
Targeted Occlusion
The in vivo median diameter of occluded arteries is significantly different between sizes of QuadraSphere Microspheres,* providing targeted occlusion.
QuadraSphere Q2 Microspheres demonstrate a median occlusion of 78 µm, a statistically significant difference compared to larger sizes of QuadraSphere.
*Swine liver embolization model study performed for Merit Medical. QuadraSphere Microspheres prepared in 50/50 mixture of saline/contrast.
Angiographies of hypervascularized tumor pre- and post-embolization illustrate the ability of QuadraSphere Microspheres to perform a targeted embolization.
Experience the Power of Conformability
QuadraSphere Microspheres are soft and easily conform to the vessel lumen for complete occlusion:
- Decreasing the risk of vessel recanalization1
- Enabling greater tumor necrosis2,3
- Providing optimal contact between the vessel wall and microsphere surface1,4
- Enhancing the embolic effect, reducing the amount of product needed to reach embolization endpoint1
Established
QuadraSphere Microspheres are a recognized and accepted platform for targeted liver embolization. QuadraSphere Microspheres are indicated for:
- Hepatoma
- Arteriovenous Malformations (AVM)
- Hypervascular Tumors (HVT)
Super-Absorbent Polymer
Referred to as super-absorbent polymer (SAP) microspheres, QuadraSphere Microspheres are packaged dry, but once exposed to aqueous-based media, they swell to approximately 4x the size printed on the product label.
References
- Bilbao JI, de Luis E, Garcia de Jalón JA, et al. Comparative study of four different spherical embolic particles in an animal model: a morphologic and histologic evaluation. J Vasc Interv Radiol 2008 Nov;19(11):1625-38.
- Lee KH, Liapi E, Vossen JA, et al. Distribution of iron oxide-containing Embosphere particles after transcatheter arterial embolization in an animal model of liver cancer: evaluation with MR imaging and implication for therapy. J Vasc Interv Radiol 2008 Oct;19(10);1490-6.
- Wáng YXJ, De Baere, Idée JM, et al. Transcatheter embolization therapy in liver cancer: an update of clinical evidences. Chin J Cancer Res 2015;27(2):96-121
- Van Malenstein H, Maleux G, Vandecaveye V, et al. A randomized phase II study of drug-eluting beads versus transarterial chemoembolization for unresectable hepatocellular carcinoma. Onkologie 2011;34(7):368-76.
Documents
Current Brochures
Order Information
Catalog Number | Expanded Family Name | Size Range | Expanding Range | Delivery System | Delivery System Size | Color | Carrier Solution | Volume | Sterilization | Latex Free | HCPCS Code | Shipping Box Qty | GS1 | GTIN Unit | GTIN Carton | GTIN Shipper |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
V125QS | QuadraSphere® Microspheres | 20-40 µm | 80-160 µm | Vial | 10 mL | Gray | Dry | 25 mg | Gamma | Yes | ||||||
V225QS | QuadraSphere® Microspheres | 30-60 µm | 120-240 µm | Vial | 10 mL | Orange | Dry | 25 mg | Gamma | Yes | No Applicable Code | 1 | ||||
V325QS | QuadraSphere® Microspheres | 50-100 µm | 200-400 µm | Vial | 10 mL | Light Green | Dry | 25 mg | Gamma | Yes | No Applicable Code | 1 |