Categories
Procedure
Features & Benefits
The C2 CryoBalloon® Ablation System delivers precise, controlled cryoablation for endoscopic treatment of Barrett’s Esophagus with dysplasia and Gastric Antral Vascular Ectasia (GAVE). Standard and Pear-shaped catheter designs that reach tubular structures, gastroesophageal junction (GEJ), and lesions big and small. Physicians can selectively target and ablate diseased tissue while sparing healthy tissue using nitrous oxide (N2O) to cryogenically freeze and cause necrosis to the target tissue for treatment.
C2 CryoBalloon 180 Catheter
Effectively treats long-segment Barrett‘s esophagus while maintaining the flexibility, accuracy, and visibility of our focal catheter.
C2 CryoBalloon Focal Catheter
For precise, targeted, short segment Barrett’s esophagus, the C2 CryoBalloon treats tissue at a cellular level.
Why Cryoablation
Cryoablation causes minimal structural damage to the treated tissue, ultimately preserving the tissues collagen matrix structure. Cryoablation has a low adverse event rate, including strictures and bleeding. Patients also report significantly less post-procedural pain and need for narcotic medication compared with RFA. (Canto, M. I., Shin, E. J., Khashab, M. A., Montgomery, E. A., Wolfsen, H. C., Wallace, M. B., Greenwald, B. D., Dumot, J. A., Abrams, J. A., Lightdale, C. J., Wolfsen, H. C., & Shaheen, N. J. (2018). Multifocal nitrous oxide cryoballoon ablation with or without endoscopic mucosal resection for treatment of neoplastic Barrett’s esophagus (with video). Gastrointestinal Endoscopy, 88(3), 438–446.e2.)
Product Comparison
- A treatment for long-segment Barrett‘s esophagus with proven reduction in post-treatment patient pain.2
- Lower post-treatment mean peak-pain score and duration of pain when compared to radiofrequency ablation (RFA).2
Documents
Current IFU
C2 CryoBalloon® Ablation System – IFU (English) 
Current Brochure
C2 CryoBalloon® Ablation System – Brochure (English)
The Instructions for Use (IFU) provided on this page are for general information purposes only. Please refer to the IFU provided with the actual product for indications, contraindications, warnings, precautions, and directions for use.
Order Information
REFERENCES
1. Compared to cryoablation using focal catheter. Data on file.
2. van Munster et al. 2018. “Focal Cryoballoon versus Radiofrequency Ablation of Dysplastic Barrett’s Esophagus: Impact on Treatment Response and Postprocedural Pain.” Gastrointest Endosc 88, no. 5 (Nov): 795–803.e2. doi: 10.1016/j.gie.2018.06.015.
Before using any of the products mentioned, refer to Instructions for Use for indications, contraindications, warnings, precautions, and directions for use.
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