QuadraSphere Microspheres are calibrated, spherical, hydrophilic microspheres made from 2 monomers (vinyl acetate and methyl acrylate) that combine to form a copolymer (sodium acrylate alcohol copolymer). This proprietary design allows a more complete and targeted occlusion of the blood vessels feeding a hypervascular tumor or arteriovenous malformation.

QuadraSphere Microspheres’ unique properties enable targeted occlusion for effective embolization in the following ways:

• Targeted: Flow directed due to spherical shape
• Absorbing: Rapidly absorbs aqueous based solutions like contrast media and 0.9% saline solution. The spheres are negatively charged, which allows them to bond ionically with positively charged aqueous based solutions.
• Conforming: Compresses in the vessel lumen, providing more surface contact with vessel intima.
• Expanding: Expands up to four times the stated dry diameter when hydrated with non-ionic aqueous solutions before delivery.

QuadraSphere Microspheres are cleared by the FDA for the embolization of hypervascular tumors and arteriovenous malformations (AVMs).