New Video Showcases Radial Portfolio

A new video showcases our extensive Radial portfolio, which includes products that support your radial procedure every step of the way – from preparation to hemostasis – providing procedural efficiency.  The new video highlights the benefits of radial access and includes our newest radial products, including the PreludeEASE™ Hydrophilic Sheath Introducer and the Rad Board® Radial Arm Board. To watch the new video, visit “Our Radial Products” on the Think Radial page.

Scion Clo-Sur P.A.D. to be included in Companion to Braunwald’s Heart Disease Textbook

Merit Medical was recently notified that an illustration featuring the Scion Clo-Sur P.A.D will be included in Cardiovascular Intervention: A Companion to Braunwald’s Heart Disease, first edition by Deepak L. Bhatt MD. The book’s publication date is May 2015. Braunwald’s Heart Disease is a textbook of cardiovascular medicine. It is updated frequently to include the latest clinical trials, new research, and updates on clinical practice for practitioners, physicians-in-training, and students of cardiology. The author, Deepak L. Bhatt MD, MPH, FACC, FAHA, FSCAI, FESC is a Professor of Medicine, Harvard Medical School and Executive Director, Interventional Cardiovascular Programs, Brigham and Women’s Hospital Heart & Vascular Center, in Boston, Massachusetts. He has authored or co-authored over 700 publications. Dr. Bhatt is the Editor of the peer-reviewed Journal of Invasive Cardiology, Chief Medical Editor of Cardiology Today’s Intervention for healthcare professionals, and Editor-in-Chief of the Harvard Heart Letter for patients.

The Clo-Sur P.A.D. is a non-woven topical pad made with a proprietary polyprolate, a positively-charged material that reacts with negatively-charged red blood cells to accelerate clotting. The Clo-Sur P.A.D. promotes hemostasis and the Clo-Sur PLUS P.A.D.™ promotes hemostasis and is indicated as an antimicrobial barrier.

The book’s illustration depicts how the Clo-Sur P.A.D.’s positive charge which reacts with negatively charged red blood cells to accelerate clotting in the tissue tract.

To learn more about the Clo-Sur P.A.D., watch the product video or Contact Us.

Mark Heninger
Senior Product Manager

ONE Snare® Endovascular Snare System Microsnare Sizes Receive FDA 510(k) Clearance

I’m pleased to announce that ONE Snare microsnare sizes are FDA 510(k) cleared and available for sale in the United States.

ONESnareThese new ONE Snare product configurations are available in loop diameters of 2 mm, 4 mm and 7 mm with a 2.3F-3F snare delivery catheter. The ONE Snare suite of endovascular snares are now available in fifteen kit configurations with ten loop diameters ranging from 2 mm to 35 mm. These sizes complete the suite of ONE Snare product configurations and give physicians additional choice and options when foreign body manipulation or retrieval procedures arise.

Designed with accuracy and reliability in mind, the ONE Snare and the EN Snare® Endovascular Snare Systems go hand-in-hand to provide physicians with both single loop and triple loop options to help meet any clinically-challenging case that may arise, because having options matters.

To learn more, visit the ONE Snare product webpage.

Jesse Hansen
Marketing Director

Merit Medical Exhibiting at 2014 VEITH Symposium in New York on November 18-22

Merit Medical is proud to support the VEITH Symposium, celebrating its 41st year, in New York City. Attendees for this meeting include vascular surgeons, interventional radiologists, interventional cardiologists and other vascular specialists.

If you plan to attend VEITH, please make sure to stop by our booth to learn more about our latest innovations from access to intervention. Some of these unique devices include:

From preparation to intervention, our products are designed to help achieve the clinical, economical, and procedural efficiency that is essential for delivering the best possible care.

Look forward to seeing you at VEITH!

Jesse Hansen
Marketing Director

Merit Medical Donates PD Catheters for Stuffed Animals to Comfort Young Patients

image1-16Recently we heard from a pediatric nephrology nurse at the Johns Hopkins Children’s Center who requested a number of our pediatric Flex-Neck® peritoneal dialysis catheters on behalf of Tubie Friends™. They wanted to give their young patients a furry friend who has a PD catheter just like theirs, with hopes of making the process less frightening. We were more than willing to donate to this worthy cause.

The sales and marketing staff at Merit Medical worked together to provide the requested catheters. We were pleased to see the end result, this adorable PD Bunny pictured here. The PD nurse said the response from the patient was priceless: “It looks just like me!”

image2-18Tubie Friends is a non-profit group that was founded by two mothers of children with implanted feeding tubes. These moms wanted to make life easier for children who are receiving treatment through PD catheters or tubing.

Tubie Friends are not only donated to patients but also sold to raise funds for the organization. These comforting toys have been used as a teaching tool for family, friends, school nurses, and caregivers to help children become comfortable and less fearful of implanted tubes and catheters.

If you’d like more information about Merit Medical’s complete line of peritoneal dialysis products, please Contact Us.

Lynette Ruppel
Senior Product Manager


HepaSphere Microspheres Absorb Both Mechanically and Ionically for Optimal Doxorubicin Loading

HepaSphere Microspheres are super absorbent polymer (SAP) microspheres made from vinyl acetate and methyl acrylate that combine to form a copolymer–sodium acrylate alcohol copolymer.

How do they work? HepaSphere Microspheres have the ability to load doxorubicin two ways: mechanically and through ionic interaction. Through mechanical interaction, HepaSphere Microspheres rapidly absorb aqueous solutions such as contrast media, saline, or reconstituted doxorubicin HCI* and expand up to four times the stated dry diameter when hydrated. A recent study found that SAP have the ability to load 50 and 75 mg doxorubicin with ease of handling and optimal efficiency through dry loading.1

* Doxorubicin HCl used with HepaSphere Microspheres should be reconstituted with saline; never use pure water.

High Drug Loadability

MECHANICAL INTERACTION – HepaSphere Microspheres act as a reservoir and mechanically absorb aqueous solutions.

HepaSphere Mechanical Interaction

IONIC INTERACTION – The doxorubicin is loaded and eluted by a reversible ionic exchange mechanism.

HepaSphere Ionic Interaction

In the ionic interaction, the dry HepaSphere’s anionic polymer is negatively charged and absorbs the doxorubicin, which is positively charged or cationic.

Increased Tumour Necrosis

In a study on an animal model, the doxorubicin loading and efficiency of polyvinyl alcohol sodium acrylate copolymer microspheres were tested. The results found that Merit’s microspheres “can be efficiently loaded with doxorubicin” and that “histopathological tumour necrosis at 7 days was more prominent in the group treated with doxorubicin-loaded microspheres than in the bland embolisation group.” Both in vitro and in vivo studies showed a high drug loadability and sustained drug release over time, high intratumoural doxorubicin concentrations at each time point, and on histopathology, increased tumour necrosis.” 2

Efficient Loading

A study of doxorubicin eluting beads shows the difference in loading between HepaSphere Microspheres and another embolic brand. The study found that the competitor’s bead loaded only on the outer 20 microns of the bead. HepaSphere loads doxorubicin throughout the sphere.

HepaSphere Microspheres load doxorubicin throughout the microsphere.

HepaSphere bead

Competitor Bead – Confocal laser scanning microscopy images of dox-loaded beads (25 mgm/mL 500-700 micron bead). Image (below) shows progressive sections from the outside inwards at 10 micron intervals.3

HepaSphere bead competitor

For more information on HepaSphere Microspheres and loading of doxorubicin, explore the product’s website page or see our step-by-step reference guides:

HepaSphere Microspheres Lyophilized Doxorubicin Mixing Chart

HepaSphere Microspheres Presolubilized Doxorubicin Mixing Chart

The Merit Medical Embolics Team is ALWAYS available to answer any questions about our Embolics Portfolio. Contact Us.

Antonio Rivera, BSRT, MSHS

Global Product Manager


HepaSphere Microspheres are not approved or available for sale in the United States. In the European Union, HepaSphere Microspheres are indicated for use in embolisation of blood vessels with or without delivery of doxorubicin HCl for therapeutic or preoperative purposes in the embolisation of hepatocellular carcinoma and the embolisation of metastases to the liver.


  1. Liu DM, Kos S, Buczkowski A, Kee S, Munk PL, Klass D, Wasan E. Optimization of doxorubicin loading for superabsorbent polymer microspheres: in vitro analysis. Cardiovasc Intervent Radiol. 2012 Apr;35(2):391-8.
  2. Lee KH, Liapi EA, et al. Doxorubicin-loaded QuadraSphere Microspheres: Plasma pharmacokinetics and intratumoral drug concentration in an animal model of liver cancer. Cariovasc Intervent Radiol. JUN 2010; 33(3):576-582.
  3. Lewis LL, Gonzalez MV, Leppard SW, Brown JE, Stratford PW, Phillips GJ, Lloyd AW. Doxorubicin eluting beads-1: Effects of drug loading on bead characteristics and drug distribution. J Mater Sci. Sep 2007;18(9):1691-1699.